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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you have any questions or concerns about taking Cialis, always consult your doctor or pharmacist.

C.

Cialis (tadalafil) can interact with certain foods and beverages, including grapefruit, grapefruit, and grapefruit juice. Discuss with your doctor, which drugs you are taking before using with your doctor's office medicine cabinet ( Verify the drug cabinet is checked regularly).

If you are taking or have recently taken any other medications, follow the instructions given by your doctor or the package insert for your medication. Contact your doctor if you start or stop any medication at the same time as Cialis.

Although Cialis is known as a phosphodiesterase type 5 (PDE5) inhibitor, it may cause side effects in some people. The common side effects include flushing, headache, heartburn, indigestion, and nasal congestion. If you experience severe symptoms, stop taking Cialis, or other drugs that may interact with it, should you exceed the recommended dose.

Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

Read the "Patient Information Leaflet" single file for more information about tadalafil generic and related medications.What is Tadalafil?

Tadalafil, the active ingredient in the brand name Cialis, is a medication used to treat erectile dysfunction (ED) and pulmonary hypertension (BPH). It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing blood vessels and increasing blood flow to the penis during sexual stimulation. By inhibiting PDE5, Tadalafil increases the amount of tadalafil in the body.

Tadalafil is available as generic in the dosage form of Tadalafil citrate. It is used with a dose (Strength) of 30 mg taken as needed, with or without food.

How does Tadalafil (Cialis) work?

Tadalafil citrate belongs to a group of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by inhibiting the enzyme that breaks down cGMP (a substance in the penis). This causes the blood vessels to relax, and blood to flow into the penis, where it can cause an erection. Tadalafil works in about 25% of people with ED. It does not protect against sexually transmitted diseases - including HIV and hepatitis B.

For BPH, Tadalafil may be used as needed, usually during sexual activity to achieve and maintain an erection. Unlike erectile dysfunction, tadalafil citrate does not usually cause pain or decrease in libido unless it is caused by a medical condition. It can also cause side effects such as headache, flushing, nasal congestion, and indigestion. Consult your doctor before taking Tadalafil generic if you are also taking finasteride while taking finasteride.

How should tadalafil be taken?

Before taking tadalafil (Cialis), your healthcare provider should ensure you take the medication exactly as your doctor has directed. You may take it either at any time of the day or on an as needed, usually at least 30 minutes before sexual activity. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. For BPH, take it at the same time each day.

How long does tadalafil work?

Tadalafil may work to help you get an erection as you get an erection. It does not usually cause pain or bleeding in your penis for at least 30 minutes after taking it. To treat, your healthcare provider may recommend taking tadalafil 2 times daily for 30 minutes to an hour before sexual activity.

How should Tadalafil be taken?

Tadalafil may be taken with or without food.

Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

  • If you are allergic to any of the ingredients in Cialis Together
  • If you have severe heart, liver or kidney problems
  • If you have blood pressure concerns
  • If you have non-arteritic anterior ischemic optic neuropathy
  • If you are taking riociguat
  • If you have other penis-related issues (deformation or painful erections)
Always read the instructions included with Cialis Together before taking it. If you do not find psychologist support in the product, check with your doctor, Nurse or pharmacist.

If you are taking riociguat your doctor may be advised to change the dose of Cialis Together from Cialis Together of your usual prescribed size. Take the tablet about one hour before you can be sure that you are getting enough medication for the treatment you are looking for. You should get an erectile dysfunction test at least 30 minutes before having sex, even if you are not taking tablets.

Side Effects

Cialis Together tablets can cause some side effects. However, they are not experienced by all the people who take them. If any of the side effects are severe or persistent, talk to your doctor, Nurse or pharmacist.

If you experience any of the following serious side effects, you should seek immediate medical attention:

  • Allergic reactions
  • Swelling of the face, lipsesesme or mouth
  • Difficulty in breathing
  • Erection that lasts more than 4 hours

If you experience any of the following health problems, talk to your doctor, Nurse or pharmacist before taking any of the Cialis Together tablets.

  • Stomach pain
  • Yellowing of your skin and eyes
  • If you experience any of the following health problems, speak to your doctor, Nurse or pharmacist before taking any of the Cialis Together tablets.

Warnings

For medicines and medical advice major side effects may be expected that may not be immediately but that you have.

Suspensionless sexual activity can sometimes cause serious problems when unintended. This is more likely to be if there is a known cause of the problem but not always. If you have not already done these things, you should do more than not enough before you can take Cialis Together but still about the problem is a bigger problem to have which you are unlikely to be able to help. These problems may not improve as much as expected but they may keep happening.

For medical advice this is the most important advice you should do in front of your health professional. They will be able to advise you if you are safe to do these things but will also help you to understand how to get the problem right.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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This prescription drug has been shown to cause some mild side effects. They include:

  • Painful erections
  • Hurtful sexual thoughts

If you experience changes in your heart rate or chest pain during sex, contact your health care provider immediately.

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  • Sudden dizziness
  • Sudden decreased interest in sexual activity
  • Sudden not feeling or being sexually excited